小鼠活動力滾輪 Running Wheel

The Columbus Instruments Mouse Home Cage Running Wheel measures spontaneous activity in a voluntary free-spinning running wheel. The wheel is constructed to fit universally into most typical "shoebox" style cages (cage is not included with the system). Each wheel has a magnetic indicator and a hall effect sensor that connects to a computer interface and records wheel revolutions at user-specified intervals. Windows software is included for installation on a customer supplied PC. Data can be viewed in real time and exported into a CSV format at the end of the experiment.

The wheel is designed to fit universally into most home cages provided that the wire lid has a flat area measuring 2 inches (5.1 cm) x 4 inches (10.2 cm) and has a ceiling height of 5.5 inches (14 cm). The Wheel Counter Interface has inputs for 8 wheel sensors and multiple counters can be daisy chained together to provide a maximum of 128 wheel inputs.

Polycarbonate Wheel and support

Windows Software Included

Maximum of 128 wheels connected to a single PC

Fits inside most typical home cages

Wheel diameter of 4 inches (10.16 cm)

Interior diameter of 3.625 inches (9.2 cm)

Wheel with of 2 inches (5.1 cm)

The effects of voluntary wheel running on neuroinflammatory status: Role of monocyte chemoattractant protein-1
Lindsay J. Spielman , Mehrbod Estaki , Sanjoy Ghosh , Deanna L. Gibson , Andis Klegeris
Molecular and Cellular Neuroscience, Available online 11 January 2017


Skeletal muscle metabolic adaptations to endurance exercise training are attainable in mice with simvastatin treatment
William M. Southern, Anna S. Nichenko, Daniel D. Shill, Corey C. Spencer, Nathan T. Jenkins, Kevin K. McCully, Jarrod A. Call
PLOS ONE, Published: February 16, 2017 https://doi.org/10.1371/journal.pone.0172551


Exercise-induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism
Jin Zhang, Paloma Valverde, Xiaofang Zhu, Dana Murray, Yuwei Wu, Liming Yu, Hua Jiang, Michel M Dard, Jin Huang, Zhiwei Xu, Qisheng Tu & Jake Chen
Bone Research 5, Article number: 16056 (2017), doi:10.1038/boneres.2016.56


Metabolic Context Regulates Distinct Hypothalamic Transcriptional Responses to Antiaging Interventions
Alexis M. Stranahan, Bronwen Martin, Wayne Chadwick, Sung-Soo Park, Liyun Wang, Kevin G. Becker, William H. WoodIII, Yongqing Zhang, and Stuart Maudsley
International Journal of Endocrinology Volume 2012 (2012), Article ID 732975, 15 pages doi:10.1155/2012/732975


Mitochondrial quality control, promoted by PGC-1α, is dysregulated by Western diet-induced obesity and partially restored by moderate physical activity in mice
Nicholas P. Greene, David E. Lee, Jacob L. Brown, Megan E. Rosa, Lemuel A. Brown, Richard A. Perry, Jordyn N. Henry, Tyrone A. Washington Physiological Reports, Vol. 3, No. e12470, 15 July 2015


Storage conditions and passages alter IL-6 secretion in C26 adenocarcinoma cell lines
Diana M. Norden, Raymond Devine, Donna O. McCarthy, Loren E. Wold
MethodsX, 7 February 2015


Fluoxetine prevents the development of depressive-like behavior in a mouse model of cancer related fatigue
Diana M. Norden, Raymond Devine, Sabahattin Bicer, Runfeng Jing, Peter J. Reiser, Loren E. Wold, Jonathan P. Godbout, Donna O. McCarthy
Physiology & Behavior, Volume 140, 1 March 2015, Pages 230-235


Muscle-specific deletion of exons 2 and 3 of the IL15RA gene in mice: Effects on contractile properties of fast and slow muscles
Grant O'Connell , Ge Guo , Janelle Stricker , LeBris Smith Quinn , Averil Ma , Emidio Edward Pistilli
Journal of Applied Physiology Published 11 December 2014 Vol. no. , DOI: 10.1152/japplphysiol.00704.2014


Voluntary Wheel Running in Mice
Jorming Goh, Warren Ladiges
Cell & Molecular Biology, 2 December 2015


Ubiquinol Reduces Muscle Wasting but Not Fatigue in Tumor-Bearing Mice
Yvonne Y. Clark, Loren E. Wold, Laura A. Szalacha, Donna O. McCarthy
Biol Res Nurs September 16, 2014 1099800414543822


T-box Transcription Regulator Tbr2 Is Essential for the Formation and Maintenance of Opn4/Melanopsin-Expressing Intrinsically Photosensitive Retinal Ganglion Cells
Chai-An Mao, Hongyan Li, Zhijing Zhang, Takae Kiyama, Satchidananda Panda, Samer Hattar, Christophe P. Ribelayga, Stephen L. Mills, and Steven W. Wang
The Journal of Neuroscience, 24 September 2014, 34(39): 13083-13095; doi: 10.1523/JNEUROSCI.1027-14.2014


PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling
Suowen Xu, Chang Hoon Ha, Weiye Wang, Xiangbin Xu, Meimei Yin, Felix Q. Jin, Michael Mastrangelo, Marina Koroleva, Keigi Fujiwara, Zheng Gen Jin
Cellular Signalling, Vol. 28, Issue 3, Pages 117-124, March 2016


Loss of IL-15 receptor ? alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles
Emidio E. Pistilli, Sasha Bogdanovich, Fleur Garton, Nan Yang, Jason P. Gulbin, Jennifer D. Conner, Barbara G. Anderson, LeBris S. Quinn, Kathryn North, Rexford S. Ahima, and Tejvir S. Khurana
J Clin Invest. Aug 1, 2011; 121(8): 3120-3132.


SCD1 activity in muscle increases triglyceride PUFA content, exercise capacity, and PPARδ expression in mice
Michael P. Rogowski, Matthew T. Flowers, Alexis D. Stamatikos, James M. Ntambi and Chad M. Paton
The Journal of Lipid Research, October 2013, 54, 2636-2646.


Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice
Alexis M. Stranahan, Kim Lee, Bronwen Martin, Stuart Maudsley, Erin Golden, Roy G. Cutler, and Mark P. Mattson
Hippocampus. 2009 October; 19(10): 951-961.


Lifelong running reduces oxidative stress and degenerative changes in the testes of mice
Srinivasulu Chigurupati, Tae Gen Son, Dong-Hoon Hyun, Justin D Lathia, Mohamed R Mughal, Jason Savell, Shuan C Li, G P C Nagaraju, Sic L Chan, Thiruma V Arumugam and Mark P Mattson
J Endocrinol November 1, 2008 199 333-341


The Disease Progression of Mecp2 Mutant Mice Is Affected by the Level of BDNF Expression
Qiang Chang, Gargi Khare, Vardhan Dani, Sacha Nelson, Rudolf Jaenisch
Neuron, Volume 49, Issue 3, 2 February 2006, Pages 341-348


Moderate Physical Activity Promotes Basal Hepatic Autophagy in Diet-Induced Obese Mice
Megan E. Rosa-Caldwell, David E. Lee, Jacob L. Brown, Lemuel A. Brown, Richard A. Perry, Jr, Elizabeth S. Greene, Francisco R Carvallo Chaigneau, Tyrone A. Washington, Nicholas P. Greene
Applied Physiology, Nutrition, and Metabolism, 12 October 2016, 10.1139/apnm-2016-0280

 

原廠連結:

http://www.colinst.com/products/running-wheel-for-mouse-home-cage