產品資訊
產品資訊
產品特點
Columbus Instruments 的小鼠飼養籠用滾輪用於測量動物在自願自由旋轉滾輪中的自發性活動。此滾輪設計通用,可安裝於大多數典型的「鞋盒式」飼養籠中(系統不含飼養籠)。每個滾輪都配有磁性指示器和霍爾效應感測器,可連接到電腦介面,並以使用者設定的時間間隔記錄滾輪轉數。產品隨附 Windows 軟體,供客戶自行安裝於個人電腦上。數據可即時查看,並在實驗結束時匯出為 CSV 格式。
滾輪設計為通用型,可安裝於大多數居家籠中,前提是金屬籠蓋需有尺寸為 2 英吋 (5.1 公分) x 4 英吋 (10.2 公分) 的平坦區域,且籠內高度為 5.5 英吋 (14 公分)。滾輪計數器介面有 8 個滾輪感測器輸入埠,多個計數器可串聯連接,最多可提供 128 個滾輪輸入。
產品規格
特點與規格
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聚碳酸酯跑輪及支架
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內含 Windows 軟體
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單台個人電腦最多可連接 128 個跑輪
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適用於大多數典型居家籠
滾輪尺寸
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滾輪直徑: 4 英吋 (10.16 公分)
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內部直徑: 3.625 英吋 (9.2 公分)
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滾輪寬度: 2 英吋 (5.1 公分)
應用領域
The effects of voluntary wheel running on neuroinflammatory status: Role of monocyte chemoattractant protein-1
Lindsay J. Spielman , Mehrbod Estaki , Sanjoy Ghosh , Deanna L. Gibson , Andis Klegeris
Molecular and Cellular Neuroscience, Available online 11 January 2017
Skeletal muscle metabolic adaptations to endurance exercise training are attainable in mice with simvastatin treatment
William M. Southern, Anna S. Nichenko, Daniel D. Shill, Corey C. Spencer, Nathan T. Jenkins, Kevin K. McCully, Jarrod A. Call
PLOS ONE, Published: February 16, 2017 https://doi.org/10.1371/journal.pone.0172551
Exercise-induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism
Jin Zhang, Paloma Valverde, Xiaofang Zhu, Dana Murray, Yuwei Wu, Liming Yu, Hua Jiang, Michel M Dard, Jin Huang, Zhiwei Xu, Qisheng Tu & Jake Chen
Bone Research 5, Article number: 16056 (2017), doi:10.1038/boneres.2016.56
Metabolic Context Regulates Distinct Hypothalamic Transcriptional Responses to Antiaging Interventions
Alexis M. Stranahan, Bronwen Martin, Wayne Chadwick, Sung-Soo Park, Liyun Wang, Kevin G. Becker, William H. WoodIII, Yongqing Zhang, and Stuart Maudsley
International Journal of Endocrinology Volume 2012 (2012), Article ID 732975, 15 pages doi:10.1155/2012/732975
Mitochondrial quality control, promoted by PGC-1α, is dysregulated by Western diet-induced obesity and partially restored by moderate physical activity in mice
Nicholas P. Greene, David E. Lee, Jacob L. Brown, Megan E. Rosa, Lemuel A. Brown, Richard A. Perry, Jordyn N. Henry, Tyrone A. Washington Physiological Reports, Vol. 3, No. e12470, 15 July 2015
Storage conditions and passages alter IL-6 secretion in C26 adenocarcinoma cell lines
Diana M. Norden, Raymond Devine, Donna O. McCarthy, Loren E. Wold
MethodsX, 7 February 2015
Fluoxetine prevents the development of depressive-like behavior in a mouse model of cancer related fatigue
Diana M. Norden, Raymond Devine, Sabahattin Bicer, Runfeng Jing, Peter J. Reiser, Loren E. Wold, Jonathan P. Godbout, Donna O. McCarthy
Physiology & Behavior, Volume 140, 1 March 2015, Pages 230-235
Muscle-specific deletion of exons 2 and 3 of the IL15RA gene in mice: Effects on contractile properties of fast and slow muscles
Grant O'Connell , Ge Guo , Janelle Stricker , LeBris Smith Quinn , Averil Ma , Emidio Edward Pistilli
Journal of Applied Physiology Published 11 December 2014 Vol. no. , DOI: 10.1152/japplphysiol.00704.2014
Voluntary Wheel Running in Mice
Jorming Goh, Warren Ladiges
Cell & Molecular Biology, 2 December 2015
Ubiquinol Reduces Muscle Wasting but Not Fatigue in Tumor-Bearing Mice
Yvonne Y. Clark, Loren E. Wold, Laura A. Szalacha, Donna O. McCarthy
Biol Res Nurs September 16, 2014 1099800414543822
T-box Transcription Regulator Tbr2 Is Essential for the Formation and Maintenance of Opn4/Melanopsin-Expressing Intrinsically Photosensitive Retinal Ganglion Cells
Chai-An Mao, Hongyan Li, Zhijing Zhang, Takae Kiyama, Satchidananda Panda, Samer Hattar, Christophe P. Ribelayga, Stephen L. Mills, and Steven W. Wang
The Journal of Neuroscience, 24 September 2014, 34(39): 13083-13095; doi: 10.1523/JNEUROSCI.1027-14.2014
PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling
Suowen Xu, Chang Hoon Ha, Weiye Wang, Xiangbin Xu, Meimei Yin, Felix Q. Jin, Michael Mastrangelo, Marina Koroleva, Keigi Fujiwara, Zheng Gen Jin
Cellular Signalling, Vol. 28, Issue 3, Pages 117-124, March 2016
Loss of IL-15 receptor ? alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles
Emidio E. Pistilli, Sasha Bogdanovich, Fleur Garton, Nan Yang, Jason P. Gulbin, Jennifer D. Conner, Barbara G. Anderson, LeBris S. Quinn, Kathryn North, Rexford S. Ahima, and Tejvir S. Khurana
J Clin Invest. Aug 1, 2011; 121(8): 3120-3132.
SCD1 activity in muscle increases triglyceride PUFA content, exercise capacity, and PPARδ expression in mice
Michael P. Rogowski, Matthew T. Flowers, Alexis D. Stamatikos, James M. Ntambi and Chad M. Paton
The Journal of Lipid Research, October 2013, 54, 2636-2646.
Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice
Alexis M. Stranahan, Kim Lee, Bronwen Martin, Stuart Maudsley, Erin Golden, Roy G. Cutler, and Mark P. Mattson
Hippocampus. 2009 October; 19(10): 951-961.
Lifelong running reduces oxidative stress and degenerative changes in the testes of mice
Srinivasulu Chigurupati, Tae Gen Son, Dong-Hoon Hyun, Justin D Lathia, Mohamed R Mughal, Jason Savell, Shuan C Li, G P C Nagaraju, Sic L Chan, Thiruma V Arumugam and Mark P Mattson
J Endocrinol November 1, 2008 199 333-341
The Disease Progression of Mecp2 Mutant Mice Is Affected by the Level of BDNF Expression
Qiang Chang, Gargi Khare, Vardhan Dani, Sacha Nelson, Rudolf Jaenisch
Neuron, Volume 49, Issue 3, 2 February 2006, Pages 341-348
Moderate Physical Activity Promotes Basal Hepatic Autophagy in Diet-Induced Obese Mice
Megan E. Rosa-Caldwell, David E. Lee, Jacob L. Brown, Lemuel A. Brown, Richard A. Perry, Jr, Elizabeth S. Greene, Francisco R Carvallo Chaigneau, Tyrone A. Washington, Nicholas P. Greene
Applied Physiology, Nutrition, and Metabolism, 12 October 2016, 10.1139/apnm-2016-0280
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