產品資訊
產品資訊
冷熱板測試儀 Hot/Cold plate
產品型號: 35300
廠牌名稱: Ugo basile
新版的冷熱板可在-5至65°C間任意設定實驗溫度。
可以作為傳統的熱板使用，快速精確地進行麻醉鎮痛藥的藥物篩選；也可以用於冷痛測試，研究寒冷受體和冷觸誘發痛。
可另外選購輔助板來進行冷熱偏好相關研究
產品特點
- 一機兩用，同一設備可加熱至65度或是降溫至零下5度
- 可使用加熱模式進行常規的熱刺激疼痛實驗及其相關的治療與藥物測試
- 使用降溫模式使設備溫度達到低溫甚至零下，可用來進行冷刺激與凍傷相關與其治療手段的研究
- 機台包含了圓柱型籠具(包含蓋子)，避免長時間的實驗導致外界水氣被凝固進而影響實驗結果
- 可選配輔助板，將兩板連接成為完整的冷熱偏好實驗設備
The new Hot/Cold Plate NG offers a wide temperature range, presettable in the range -5°C to 65°C and is very quick and precise in reaching and keeping the preset temperature.
The 35300 can be used as a conventional HOT PLATE, to carry out a rapid precise screening of narcotic type analgesic drugs according to the well known Hot Plate Test devised by N.B. Eddy and D. Leinbach.
As a COLD PLATE; the Cold Plate Test is useful in studying cold receptors and cold allodynia, a phenomenon very frequently observed in chronic pain on humans.
The lid reduces humidity condensation on the plate at low temperatures. Two working modes allow for testing at fixed temperature or at increasing/decreasing temperature (RAMP).
Brand new, user friendly software, to set up the experiment and manage the results.
An “auxiliary” Hot Plate, Cat. No. 35150-002, can be supplied as an optional, useful in the training and acclimation phase, for high-throughput tests. The 35160 combo-package, which includes a 35150 Hot/Cold Plate and a 35150-002 Hot Plate, can be taken into consideration.
產品規格
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General |
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Commands |
4”3 touch-screen (resistive) |
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Read-out |
on the touch-screen |
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Power Requirement |
Universal input 85-264 VAC, 50-60Hz, 40W max. |
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Sound Level |
< 60 dB (A) |
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Operating Temperature |
18° to 25°C see paragraph 2.1.1 |
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Operation |
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Temperature |
adjustable in the range -5.0 to 65.0°C, with 0.1°C increments |
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Precision |
+/- 0.1°C |
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Mode |
hot plate, cold plate, ramp (increasing or decreasing) |
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Counting Start |
by START button or pedal switch |
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Counting Stop |
by pedal switch |
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Latency Time Counter |
up to 999.9 seconds, in 0.1 steps |
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Data Acquisition |
via X-PAD software, provided |
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Data Portability |
by USB flash drive, provided |
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TTL Output |
for temperature and counter status |
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Data |
exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive |
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Configurations |
exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive |
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Physical |
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Total Weight |
8Kg |
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Shipping Weight |
12Kg approx. |
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Dimensions |
25(w)x37(d)x47(h)cm – including restrainer |
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Packing Dimensions |
68x34x28cm |
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Warranty |
35300 is covered by a 24-month warranty |
Optional
An “auxiliary” conventional Hot Plate 35150-002 is available as optional; this self-standing unit may be used for the habituation phase before the test, thus reducing the use of the main unit to the test proper.
應用領域
The hot plate tests the pain response in animals, used in basic pain research and in testing the effectiveness of analgesics by observing the reaction to pain caused by heat.
The method, devised by N.B. Eddy and D. Leimbach in 1953 (see paragraph 8.1-Method Papers) evaluates the reaction time of mice dropped on a heated surface and thus confronted with a heat stimulus applied to the plantar surface.
Eddy and Leimbach used a behavioral model of nociception where behavior such as jumping and hind paw-licking are elicited following a noxious thermal stimulus. Licking is a rapid response to painful thermal stimuli that is a direct indicator of nociceptive threshold. Jumping represents a more elaborated response, with a latency, and encompasses an emotional component of escaping.
When a central analgesic agent is administered to the animals, reaction time is markedly increased.
The new Hot/Cold Plate 35300 has been designed to study more recently published cold receptor systems of neurons, which are not activated by cold but rather by chemicals, as well as the traditional cold receptors. These neurons are present in the CNS as well as PNS, but they are different from the neurons which sense pain.