Tetrodotoxin (TTX)

此商品僅限研究單位訂購, 個人與同行恕不提供報價

HelloBio的TTX共有2款：標準版 (含有檸檬酸, 可溶於水), 以及無檸檬酸版 (需自行調配pH 4.8的酸性溶劑)

歡迎來電洽詢, 大量訂購另有優惠

Figure 1. TTX mediated inhibition of action potential firing upon post synaptic current injection in cortical neuron

Tetrodotoxin is commonly used in electrophysiology to block excitability by inhibiting action potential firing within neurons. It is commonly applied at concentrations of 1 µM. Tetrodotoxin from Hello Bio works as expected and blocks action potential firing. For assay protocol, see #Protocol 1 in Application Notes below.

Figure 2. TTX mediated inhibition of electrically evoked EPSP and action potential within cortical neuron

Tetrodotoxin is commonly used in electrophysiology to block excitability by inhibiting action potential firing within neurons. It is commonly applied at concentrations of 1 µM. Tetrodotoxin from Hello Bio works as expected and blocks action potential firing For assay protocol, see #Protocol 2 in Application Notes below.

Figure 3. Whole-cell voltage clamp recordings made from primary cultured rat cortical neurons.

Neurons are voltage clamped with a holding voltage of -70 mV. Spontaneous miniature excitatory postsynaptic currents (SEPSCs) are recorded. 100 nM was then bath applied in the perfusate, resulting in the rapid elimination of action potential spiking.

原廠連結

Tetrodotoxin

Tetrodotoxin citrate