廠牌名稱: Ugo basile
The 37215 Analgesy-meter is the classic device to perform Paw Pressure experiments according to the Randall-Selitto method, The Ugo Basile original design dates back to the 1960s.
Typically, the Randall-Selitto method is used as a rapid and sensitive screening of analgesic and anti-inflammatory drugs.
The force is applied to the animal paw, which is placed on a small plinth under a cone-shaped pusher with a rounded tip, which does not hurt the animal. The 37215, originall designed for rats, is conveniently used also with mice; however, when lower pressure is required, we offer model 37216, with applied pressure reduced to 50% and including a special chisel-shaped pusher.
The operator depresses a pedal-switch to start the mechanism which exerts the force; when the rat struggles, the operator releases the pedal and reads off the scale the force at which the animal felt pain. Additional weights are provided, to increase the force range. The Analgesy-Meter features a low voltage synchronous motor.
The classic Analgesy-Meter can now be integrated with a specific pressure sensor and the related controller, available as optional, which upgrades the Analgesy-Meter to a fully digital device.
As the basic design is unchanged, results with the digital model are consistent with published data.
The design of the upgrade kit makes it easy to retrofit existing UB Analgesy-Meters as well. Ask for details!
|Start / Stop
|by pedal switch
3 force ranges:
37215 from 0 to 250, 500, 750 grams
37216 from 0 to 125, 250, 375 grams
|115/230 Volts, 50/60 Hz
|15 W max.
|Digital data recording
|via optional Analgesy-Meter DAQ 37215-100
|10° to 40° C
|5.4 Kg approx.
|46 x 16 x 14 cm
|55 x 45 x 36 cm
The Basile Analgesy-Meter has been designed to perform rapid precise screening of an-algesic drugs on the normal and inflamed rat paw, according to the Randall-Selitto test.
The instrument is basically a device which exerts a force increasing at a constant rate (a certain number of grams per second). This force is continuously monitored by a pointer moving along a linear scale.
The force is applied to the animal’s paw, which is placed on a small plinth under a cone-shaped pusher with a rounded tip. The plinth is made of TEFLON, which is biologically inert and has a very low friction coefficient. Thus, if the animal suddenly withdraws its paw, it slips out easily without being injured.
The operator depresses a pedal-switch to start the mechanism which exerts the force.
When the rat struggles, the operator releases the pedal and reads off the scale the force at which the animal felt pain.