疼痛測試儀 Analgesy-Meter

• 典型的Randall-Selitto式腳掌壓力測試儀器。
• 量測方式直接且敏感，可以在極短的時間內測得動物疼痛程度的相關數據。
• 主要應用於鎮痛藥還有抗發炎藥物的快速篩選。
• 儀器利用低電壓的同步馬達，操作人員可以利用腳踏板進行機器的控制。當動物開始掙扎的時候，操作員只要放開踏板，讀取動感到疼痛的相關數值。
• 機型分為適合於大鼠的37215，以及降低50%力道，適用於小鼠的37216。兩種機型無法兼用！

The 37215 Analgesy-meter is the classic device to perform Paw Pressure experiments according to the Randall-Selitto method, The Ugo Basile original design dates back to the 1960s.

Typically, the Randall-Selitto method is used as a rapid and sensitive screening of analgesic and anti-inflammatory drugs.

The force is applied to the animal paw, which is placed on a small plinth under a cone-shaped pusher with a rounded tip, which does not hurt the animal. The 37215, originall designed for rats, is conveniently used also with mice; however, when lower pressure is required, we offer model 37216, with applied pressure reduced to 50% and including a special chisel-shaped pusher.

The operator depresses a pedal-switch to start the mechanism which exerts the force; when the rat struggles, the operator releases the pedal and reads off the scale the force at which the animal felt pain. Additional weights are provided, to increase the force range. The Analgesy-Meter features a low voltage synchronous motor.

 The classic Analgesy-Meter can now be integrated with a specific pressure sensor and the related controller, available as optional, which upgrades the Analgesy-Meter to a fully digital device.

As the basic design is unchanged, results with the digital model are consistent with published data.

The design of the upgrade kit makes it easy to retrofit existing UB Analgesy-Meters as well. Ask for details!

The Basile Analgesy-Meter has been designed to perform rapid precise screening of an-algesic drugs on the normal and inflamed rat paw, according to the Randall-Selitto test.

The instrument is basically a device which exerts a force increasing at a constant rate (a certain number of grams per second). This force is continuously monitored by a pointer moving along a linear scale.

The force is applied to the animal’s paw, which is placed on a small plinth under a cone-shaped pusher with a rounded tip. The plinth is made of TEFLON, which is biologically inert and has a very low friction coefficient. Thus, if the animal suddenly withdraws its paw, it slips out easily without being injured.

The operator depresses a pedal-switch to start the mechanism which exerts the force.

When the rat struggles, the operator releases the pedal and reads off the scale the force at which the animal felt pain.

原廠連結