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Ugo basile 腳底熱刺激儀 Plantar Test (Hargreaves Apparatus)

產品型號: 37370
廠牌名稱:
產品簡介:
•腳底熱測試儀是用來測量齧齒類動物對紅外熱刺激的反應。
•量測原理是利用紅外線光源聚焦於動物腳底,按下開關,等待動物縮回受測爪,儀器自動記錄紅外線強度和持續時間。
•實驗資料會顯示在液晶螢幕上,也可存入隨身碟中,或在通過USB傳輸至電腦中。
•疼痛甩尾和冷熱板實驗算是急性疼痛耐熱的經典測量方法,且這兩種實驗至今仍然被藥理學研究採用,但是其中有一些限制。兩種方法都沒有在痛覺敏感的行為反應研究中得到運用。
•腳底測試代表了一種先進的實驗方法,它集合了所有疼痛過敏測試的優點。實驗時,受試動物不會受到束縛;另外,實驗資料記錄是儀器自動感應完成的,不會因人員因素影響其準確度。

產品特點

The Plantar Test Instrument (Hargreave’s Method) measures response to infrared heat stimulus, applied to the plantar surface.

Our Plantar Test is the original apparatus, designed in close cooperation with Prof. Ken Hargreaves, who devised the method.

 

Focus the infrared source below the Plantar surface and with the press of a button … latency to paw withdrawal and infrared intensity are recorded automatically (i.e.no manual scoring, as in other models available on the market!).

The Plantar Test represents a remarkable advance in methodology, as it combines the best features of all other methods of measuring pain sensitivity. Unique to the Plantar Test, the animal is unrestrained during experiments. Unlike other models available on the market, time latency is recorded automatically by a fiber optic sensor, without having to rely on the experimenter observation of the animal behaviour, thus avoiding unwanted experimental bias.

The Plantar Test basically consists of a movable I.R. (infrared) generator placed below a glass pane upon which the operator deposits the rat, see picture. A Perspex enclosure defines the space within which the animal is unrestrained. It is divided in three compartments, which help the operator to carry out a rapid “screening” work: up to 12 animals can be tested with no appreciable delay in between.

Proprietary to our model is a specific filter, cutting off the visible part of the light spectrum, which would disturb the animal on test and provide an unwanted clue. A feedback circuit detects false starts. Data appear on the front panel and may be exported to a USB pen-drive, or to the PC via USB; both USB pen-drive and software are included in the standard package. 

Data can be printed out on the optional panel-mount printer, or external MiniPrinter

 

產品規格

Operation  
Power Requirement Universal mains 85-264 VAC, 50-60Hz
Commands via soft-buttons
Read-out on multifunction graphic display

Print-out

 

via optional thermal MiniPrinter or panel-mount printer

Starting

 

via keys on the I.R. Vessel and on the Controller
I.R. Intensity adjustable in the interval 01-99 (in one digit steps)
Latency Time displayed on the graphic display, in 0.1s steps
Connection to PC via USB cable
Data Portability via USB flash drive provided
Calibration via appropriate I.R. Radiometer (optional)
Operating Temperature 10° to 40° C
Sound Level negligible
Physical
Dimensions 86 x 40 x 35 cm (assembled)
Weight 13.00 Kg 13Kg
Packing 98x49x47cm
Shipping Weight 27.50Kg approx.

應用領域

Determination of acute nociceptive thermal threshold in laboratory animals has primarily relied upon the tail flick and hot plate methods.

Although both methods are used frequently in pharmacological studies, they are not without limitation. In addition, neither method has been extended to investigating behavioural responses to hyperalgesia.

The Plantar Test represents a remarkable advance in methodology, as it combines the best features of all other methods of measuring pain sensitivity. Unique to the Plantar Test, the animal is unrestrained and unhandled during experiments.

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