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小鼠滾輪測試儀 Mouse Rota-Rod

產品型號: 47650
廠牌名稱: Ugo basile
滾輪實驗是運動協調方面藥物篩選的重要方法。根據 N.W Dunham 和 T.S Miya 1957年的論文。在1960年,Ugo Basile設計了第一個RotaRod滾輪儀。從此以後成千上萬的論文中引用了RotaRod滾輪儀,在業內被廣泛熟知。
Ugo在原有的基礎上經過多年研究,結合最新的動物行為學和藥理學進展,對滾輪儀進行了全面改進。外觀與之前的版本基本類似,但新型滾輪儀在具備同等的可靠質量之外添加了創新技術!
新版小鼠轉棒儀選用不銹鋼材質,方便清洗的同時當實驗動物下落後也能防止動物逃脫;超靜音運行,保證動物在安靜的環境下實驗;還配備全新的、方便快捷的軟體。通過新版軟體,操作人員可以在個人電腦上方便地管理安排實驗,並通過USB隨身碟上傳到滾輪儀。軟體會根據設置自動分類數據,結果呈現為一個樹狀結構, 類似自定義佈局,柱形圖可以根據需要拖動,用戶在測試前後均可添加指令,設定和數據能夠導出為Text、Excel或PDF格式進一步保存。新軟體能協助用戶規劃實驗,也使數據管理更方便快捷。

產品特點

  • 體積小巧,可置於桌面或推車上
  • 跑道寬達6.7公分,可容納任意品系的實驗小鼠 (包含肥胖鼠)
  • 包含定速、加/減速、變速模式可供選擇,您甚至可自行編寫訓練程序
  • 數據可直接透過USB隨身碟輸出成Excel表格,無需透過電腦

 

滾輪實驗是運動協調方面藥物篩選的重要方法。根據 N.W Dunham 和 T.S Miya 1957年的論文。在1960年,Ugo Basile設計了第一個RotaRod滾輪儀。從此以後成千上萬的論文中引用了RotaRod滾輪儀,在業內被廣泛熟知。


Ugo在原有的基礎上經過多年研究,結合最新的動物行為學和藥理學進展,對滾輪儀進行了全面改進。外觀與之前的版本基本類似,但新型滾輪儀在具備同等的可靠質量之外添加了創新技術!


新版小鼠轉棒儀選用不銹鋼材質,方便清洗的同時當實驗動物下落後也能防止動物逃脫;超靜音運行,保證動物在安靜的環境下實驗;還配備全新的、方便快捷的軟體。通過新版軟體,操作人員可以在個人電腦上方便地管理安排實驗,並通過USB隨身碟上傳到滾輪儀。軟體會根據設置自動分類數據,結果呈現為一個樹狀結構, 類似自定義佈局,柱形圖可以根據需要拖動,用戶在測試前後均可添加指令,設定和數據能夠導出為Text、Excel或PDF格式進一步保存。新軟體能協助用戶規劃實驗,也使數據管理更方便快捷。

The “Rota-Rod” technique is essential in screening drugs potentially active, or having side effects, on motor coordination. 

50 years ago Ugo Basile designed the original RotaRod, the first industrial Rota Rod, based on the 1957 paper by N.W Dunham and T.S Miya. The 47650 Rota-Rod NG (Next Generation), is an evolution of the original model and the result of many years of research in cooperation with the latest development in behavioral and pharmacological research. 

Since then, our models have been cited in thousands of scientific papers. The name we coined soon became so popular, now everybody knows this device as RotaRod!

What's new in the NG model:

Physically similar to the previous versions, it offers the same reliability, matched with innovative technology! The new model features stainless-steel trip-boxes to facilitate cleaning and confine the animals when they fall off the rod.

The Mouse RotaRod consists of five 3cm diam. cylinders, which are suitably machined to provide grip. Six 25cm diam. dividers make for five lanes, each 5.7cm wide, enabling five mice to be on the rotor simultaneously. The height to fall is 16cm.

A brand new, user friendly software, is included as standard; via the new software, the operator can easily organize the experiment on her/his PC, and upload it to the Rota-Rod via the USB key. The software automatically classifies the data, combining configuration settings with test results; the user can add information, before or after the test. Results appear in a tree-like structure, where columns can be dragged and dropped to customize the layout. Configurations and data are exported as Text, Excel or Pdf reports and can be saved to cloud via DropBox, OneDrive, GoogleDrive.

The experiment can be set and results can be monitored, also via the 4”3 touch-screen.

Remote diagnosis and internet access are provided.

The 47650 combines the same functionality of the previous version, now considered the standard, with additional new features: surprisingly silent operation, much easier experimental organization and data management.

 

 

產品規格

 

General  
Commands 4”3 touch-screen (resistive)
Read-out on the touch-screen
Power Requirement Universal input 85-264 VAC, 50-60Hz, 40W max.
Sound Level < 60 dB (A)
Operating Temperature 10° to 40° C
Operation  
Speed adjustable in the range 5-80 RPM, in steps of 1 RPM
Mode constant, ramp (accelerating), multi-step ramp (NEW!)
Rotation forward, reverse, rocking
Rotor Start/Stop on the touch-screen
Counting Start /Stop each section via its trip box
Number of Lanes 5
Trip-Box stainless-steel to ease sterilization
Drive forward, reverse, rocking
Data Acquisition via X-PAD software, provided
Data Portability by USB flash drive
TTL Output for lane status, rotation and speed
Data exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive
Configurations exported to Text, Excel or Pdf, or saved to cloud to DropBox, OneDrive, GoogleDrive
Physical  
Total Weight 11Kg
Shipping Weight 16Kg approx.
Dimensions 46(w)x28(d)x33(h)cm
Packing Dimensions 70x36x46cm

應用領域

The “Rota-Rod” technique has been originated by a 1957 paper of N.W. Dunham and T.S. Miya (see paragraph 9.1-Method Papers) and has proved to be of great value in research involving screening of drugs which are potentially active on motor co-ordination.

Ugo Basile designed the first industrial RotaRod in the 1960s. The name we coined soon became so popular, now everybody knows this instrument as RotaRod!
The Rota-Rod is the reference test to screen drugs potentially active, or having side effects, on motor coordination.

When a rat falls off its cylinder section onto the trip-box below, the plate boxes and the corresponding magnetic switch is activated, thereby recording the animal endurance time in seconds.

The display shows the actual angular speed (RPM). At the end of a run, the display shows for each animal the running time, the rotation mode and the rotation speed at the time the animal fell off, combined with information preset by the user.

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