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產品資訊

迴圈測試儀 Rotometer

產品型號: 43000
廠牌名稱: Ugo basile
迴圈測試儀是在旋轉環境中,通過磁場測量小鼠的活動情況。該儀器最大的優勢是測量自由移動的旋轉行為,小鼠不會受到約束,只是在它的頸部或尾上附帶上一粒微小的磁鐵,儀器將自動記錄它順時針或逆時針方向的旋轉。
儀器有一個透明的圓柱形罩,工作臺和控制單位組成。液晶屏可顯示旋轉數。它可連接電腦,具備USB埠,標準配備包含軟體。

產品特點

  • 無需任何穿戴式裝置,例如夾克、背心等
  • 動物行動自如,完全不需要約束或接線輔助
  • 僅需在動物身上夾一小粒專用磁鐵,且這個磁鐵可以夾在動物任何部位
  • 設備敏感,讓您不再錯過任何重要數據

 

迴圈測試儀是在旋轉環境中,通過磁場測量小鼠的活動情況。該儀器最大的優勢是測量自由移動的旋轉行為,小鼠不會受到約束,只是在它的頸部或尾上附帶上一粒微小的磁鐵,儀器將自動記錄它順時針或逆時針方向的旋轉。
儀器有一個透明的圓柱形罩,工作臺和控制單位組成。液晶屏可顯示旋轉數。它可連接電腦,具備USB埠,標準配備包含軟體。

 

下列幾種研究可使得動物有旋轉行為:
單側病變(多巴胺)
神經遞質水平不均衡(氨基丁或多巴胺)
焦慮、壓力可能導致異常行為
接觸某些藥物,藥物濫用或停用

 

 

The Rotometer is an original instrument from Ugo Basile, specifically designed for recording rotations in UNRESTRAINED MICE, by measuring the animal movements via a magnetic field detection system.

The greatest advantage to this instrument is that it measures free-moving rotational behaviour; no tether required. To quantify rotational behavior in a freely moving animal is a significant development: our model accomplishes precisely this task, using new and clever technology to count clockwise (CW) and counterclockwise (CCW) rotations in a circular open field.

Simply attach a tiny magnet (the size of a grain of rice) to the animal tail or nape and the Rotometer automatically tallies clockwise and counterclockwise rotations. For long term tests, the magnet can be injected.

The injectable magnets, encapsulated within a proven bio-compatible material, fit within syringes normally used for the injection of identification transponders. These small magnets are easy to inject in the animal’s nape and do not interfere with the animal behavior.

The mouse (or small rat) is placed on a 20cm diam. circular arena, enclosed in a clear Perspex cyinder, 25cm tall. Digital read-out shows accrued rotations. The Rotometer features Portable Memory Stick technology, USB interface, & software for connection to PC, all included in the standard package.

產品規格

General  
Commands via “soft keys”
Starting via command key
Read-out multifunction graphic display
Print-Out By optional thermal MiniPrinter 57145
Power Requirement Universal input 85-264 VAC, 50-60Hz, 40W max.
Sound Level < 60 dB (A)
Operating Temperature 18° to 40° C
Connection to PC via USB connector type B
Data Portability via USB flash drive, provided
Physical  
Total Weight 3.5Kg
Shipping Weight 7Kg approx.
Dimensions 25(w)x37(d)x16(h)cm (without restrainer)
Dimensions (restrainer) 20cm diam. x 25(h)cm  
Packing Dimensions 68x34x28

應用領域

The Rotometer is widely used in research on motor assessment tests. Rotometer is also used in traumatic and acquired brain injury research and spinal cord injury research.

There are several well-characterized causes for animals to exhibit rotational behavior:

• Uneven/unilateral higher expression of levels of neurotransmitters (such as GABA or dopamine). Some brain tumors can cause aberrant expression levels to occur. Injury may also interfere with proper neurotransmitter expression, and/or cause some localized change in neurotransmitter expression
• Developmental anomalies can also cause rotational behavior
• Anxiety/stress may cause this aberrant behavior
• Exposure to some drugs, or drug abuse, or withdrawal from some drugs, all may have rotational sequelae.
• Physical lesions also can cause rotational behavior in an animal 

To quantify rotational behavior in a freely moving animal is a significant development

 

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