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位置喜好測試箱 Conditioned Place Preference (CPP)

產品型號: 42552/3
廠牌名稱: Ugo basile
Ugo Basile位置喜好測試箱(CPP)主要用於評估大、小鼠藥物濫用潛在威脅和藥物的副作用,是藥物精神依賴性評價的經典實驗模型。該實驗常常配合軌跡追蹤軟體使用。
該實驗系統是一個兩隔間的箱子,兩隔間壁的顏色、圖案,底板的圖案、質地各異。底板可互換,因此,實驗人員可方便的調整;每個實驗箱包括4塊可互換的底板(方形和圓形圖案)。

產品特點

  • 包含可替換的牆壁情境花紋
  • 地板亦可配合情境更換,使動物進行實驗時獲得不同觸感
  • 灰色的箱體,針對白鼠或黑鼠皆有強烈對比

 

Ugo Basile位置喜好測試箱(CPP)主要用於評估大、小鼠藥物濫用潛在威脅和藥物的副作用,是藥物精神依賴性評價的經典實驗模型。該實驗常常配合動物軌跡追蹤軟體使用。

此系統是一個兩隔間的箱子,兩隔間壁的顏色、圖案,底板的圖案、質地各異。底板可互換,因此,實驗人員可方便的調整;每個實驗箱包括4塊可互換的底板(方形和圓形圖案)。
 

 

The new Ugo Basile Conditioned Place Preference (CPP) cage is a 2-compartment box to evaluate the abuse potential of substances and the motivational effects of drugs in mice or rats. 

The box includes the contextual cues required by the experimental paradigm:

  • 4 interchangeable floors with square or circular patterns
  • 3 sets of walls

The new CPP box has been designed and optimized for use with any video-tracking software or visual scoring.

The 2 compartments differ for the walls colour and patterns and for the floor patterns and texture. 

 

Both the floors and the wall contexts are interchangeable so that the visual and tactile difference between the 2 compartments can be easily adjusted by the scientist: replaceing the walls is quick and easy, hence on request we can provide customized sets of walls, with different pattern or texture.

產品規格

Physical  
External Dimensions (handles excluded)

42552 Rat Cage:      63x32x35(h)cm  

42553 Mouse Cage: 35x18x29(h)cm 

Internal Dimensions (of each compartment)

42552 Rat Cage:      30x30x30(h)cm  

42553 Mouse Cage: 16x15x25(h)cm 

Patterned Floors 4 interchangeable floors for each cage
Context Walls 2 interchangeable context kits provided with each cage (striped and checkered)
Shipping Weight

42552 Rat Cage:      22Kg

42553 Mouse Cage: 10Kg

Packing Dimensions

42552 Rat Cage:      80x46x56cm

42553 Mouse Cage: 36x55x45cm

應用領域

The CPP paradigm provides information on the rewarding or aversive effects of visible and tactile contextual cues associated with drugs. 

This technique has acquired great popularity in research studies involving addiction, being much easier, if compared to drug self-administration procedures. 

First, the animal is conditioned to identify one of the two compartments with the drug experience. Then the time spent in each compartments is measured; preference or
aversion to the drug-paired compartment, hence rewarding/aversive properties of drugs, can be easily deducted.

The CPP test only requires the animal to carry out a simple operation (i.e. move from one compartment to the other) to approach or avoid the drug-paired compartment; the animal is expected to spend more time in the drug-paired compartment, if the drug experience produced a positive effect.

 

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