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大小鼠主動/被動迴避實驗系統 GEMINI™ Avoidance System

產品型號:
廠牌名稱: San Diego Instruments
San Diego Instruments的 GEMINI 大小鼠主動/被動迴避實驗系統為一套多合一的迴避實驗系統,包含了主動及被動迴避實驗所需的一切硬體與軟體,並且大鼠與小鼠皆能使用,與它牌產品相比,San Diego Instruments 的GEMINI系統一套設備即可滿足您的所有迴避實驗需求。

產品特點

  • 一部電腦最多可連接最多8部GEMINI迴避系統
  • 迴避實驗中的任何參數皆可由使用者進行設定與控制
  • 系統使用USB與電腦進行連接,無需特殊規格的專用介面卡
  • 每個實驗箱皆可獨自開始或結束實驗,確保實驗條件一致性
  • 箱內機關皆可透過使用者進行控制,包含了LED照明燈、刺激/提示音喇叭、電擊網以及靜音自動門
  • 只需更換自動門板即可切換成另一種動物的實驗箱,無需兩套不同的設備

 

San Diego Instruments的 GEMINI 大小鼠主動/被動迴避實驗系統為一套多合一的迴避實驗系統,包含了主動及被動迴避實驗所需的一切硬體與軟體,並且大鼠與小鼠皆能使用,與它牌產品相比,San Diego Instruments 的GEMINI系統一套設備即可滿足您的所有迴避實驗需求。

GEMINI 的獨特設計能讓您僅憑一部電腦同時控制最多8個系統。此外,系統使用USB與電腦作連接,無需特別規格的介面卡,因此你可以使用桌電或是筆電進行操作與控制 。

GEMINI 迴避實驗系統重點特色

硬體組裝容易,無需專門電腦工程師進行

最新款的GEMINI透過USB與電腦進行連接,隨插即用,因此無需加裝專用的介面卡進行電腦與儀器的連接,您可以自由選擇想要使用的電腦種類,桌上型或筆記型電腦皆可使用。

全世界最有彈性的市售迴避實驗儀器

最新版的 GEMINI 軟體可以提供您最大的彈性,您不僅可以設定任何的實驗參數與流程,您亦可將這些設定全部儲存,下一次進行全新的實驗時讀取設定並修改即可,數據以Microsoft資料庫的型式儲存在您的電腦中,可匯出成多種形式,數據可匯出成TXT、CSV、TAB等常見格式。

其他特色:

  • 開始與結束實驗為2個不同的空間,避免取出動物時造成干擾
  • 多種機關與提示供您設計實驗
  • 使用紅外線光柵偵測動物所在,避免假訊號產生
  • 可調整延遲時間的非條件刺激 (Unconditioned Stimulus),避免動物抓到刺激節奏
  • 設備兼用於大鼠與小鼠,無需兩套設備 (需更換電擊網)
  • 不規則的電刺激方式,避免動物學習電刺激安全區域
  • 靜音閘門可確保動物專注在提示音跟燈上,而非門的開啟關閉
  • 可進行無助行為實驗 (Learned Helplessness Behavior)
  • 可選配較為溫柔的噴氣刺激裝置

SDI’s GEMINI active and passive avoidance system was designed specifically to test active avoidance and passive avoidance in rats and mice. Unlike many others, GEMINI’s hardware and software have been developed for the sole purpose of your avoidance study.

GEMINI’s unique design allows you to run up to 8 independently operated stations directly from your laptop using a standard USB.  In addition, by allowing you to define a complete study in advance, GEMINI eliminates run time data entry that could affect the accuracy of your results.

When defining your study, the avoidance testing protocol definitions will offer you multiple cues that can be used individually or in combination to test passive avoidance and active avoidance.  The sound cue offers a broad range of options as you can set any frequency or white noise necessary. Further, the unconditioned stimulus is delivered by SDI’s proprietary Shocker, which scrambles the shocks to prevent the subject from learning the pattern and therefore avoiding the shock stimulus.

GEMINI Avoidance System Highlights:

Setup GEMINI Stations with Limited Technical Knowledge

Your apparatus will connect directly to your PC through a standard USB interface.  If you use multiple stations, connect them just as easily using standard USB hubs. 

Monitor Learned Helplessness Behavior

GEMINI™ is an ideal choice to study learned helplessness behavior, in addition to active and passive avoidance. If your study calls for learned helplessness testing, use GEMINI™– the system built for it.

The Most Flexible Active and Passive Avoidance Software Available

GEMINI’s latest software gives you more flexibility and accuracy than ever. Not only is all of your data saved in one, easily accessed file—but you can define your complete study in advance by pre-assigning animals to specific stations for each session, and then assigning a predefined protocol to every test session. 

The software will automatically record your session data and keep it all together in the study’s single file. When you are ready, display your data right on your computer monitor or choose to export it with one click to Microsoft® Excel or to a delimited file type(TAB, CSV, etc.). Other software features include:

  • Consistent Results with Protocol Definitions

GEMINI’s Protocol Definitions control the cues, shock level, and duration of shock. Another key feature is the setting of the Inter-Trial intervals either for fixed durations or random durations, which prevents the subject from determining a pattern. When you save your Protocol Definitions and reuse them in multiple studies, you’ll save time by eliminating redundant data entry and will also ensure the consistency of your results.

  • Define Your Study in Advance

Make sure you collect the most accurate data possible by defining each of your planned test sessions. You will be able to plan session parameters, set subject identifiers, assign subjects to specific test stations, and specify subject parameters such as dose level.  To keep from losing any critical data, it will all be stored in a single file format.

  • Automatically Run Sessions

Defining your study in advance not only saves you time by automating sessions, but eliminates run time decisions and data entry that can cause mistakes. You’ll also ensure your results are tightly coupled to your predefined subject identifiers. Simply follow the GEMINI software instructions to execute the test session.

  • Export Directly to Microsoft® Excel (or any delimited file type)

The Gemini software makes table formatted results available for direct export to Microsoft® Excel or to a delimited file type(TAB, CSV, etc.) and automatically identifies data by column headers.  Since the data is exported from a single file, you won’t lose critical information and you’ll save time by removing the need to aggregate multiple single files and possibly reformat them again.

Start and Stop Stations Independently

Continually test animals by running each GEMINI chamber individually.  Loading and unloading animals into individual chambers does not affect the operation of other stations.

Maximize Your Options with Multiple Cues

Using the GEMINI software, select your desired cues and the duration of each. This feature provides you with the maximum flexibility in protocol design.

Choose from two light cues: House Light and Cue Light, and/or sound cues with the ability to define the exact frequency, or white noise that you want—creating virtually unlimited options.  All cues can be used individually or in combination to test passive avoidance, learned helplessness, and active avoidance. 

No False Crossing Errors

GEMINI stations have 8 photobeams on each side which accurately locate the animal. The photobeams can also be disabled near the Auto Door to make sure the animal has fully entered a compartment.  This feature will end false crossing errors.  Systems without this feature—or fewer beams—have been known to record exploratory behavior as a crossing, affecting the accuracy of results.

Delay Your Unconditioned Stimulus

Make sure your passive avoidance test results are not tainted by delaying the onset of your unconditioned stimulus (US), either foot shock or air puff.  When your US is not delayed, the subject’s learning ability can be affected by inadvertently tying the US to the gate closing.

One System that Works for Both Rats and Mice

Change your grid floors in under five minutes and avoid the need for two distinct systems.

Scrambled Shock Provides More Accurate Responses

The SDI animal shocker – a solid state feedback-controlled, constant current shocker uses 8 unique outputs to scramble the shock across the grid floor.  Scrambling the shock prevents the animal from determining a pattern and leads to more accurate responses.

In addition, GEMINI ’s shocker is the only one of its kind to display the actual current being administered to the subject—bringing clarity and accuracy to your research. 

Ensure Subjects Respond to the Right Cues

GEMINI’s quiet Auto Door helps to keep your subject from attaching the cue to the closing of the door in passive avoidance tests. In addition, the door closes by gravity, assuring the animal will not be injured while in the box.

Kinder, Gentler Unconditioned Stimulus

The Gemini System offers an alternative air puff unconditioned stimulus. This is a kinder and gentler unconditioned stimulus.

GEMINI Avoidance System Components

  • Active & Passive Avoidance Software (on USB stick)
  • Driver Software (on USB stick)
  • Test station with 2 chambers and grid floor for rats (or mice), 16 photobeams, 2 LED “house” and 2 “cue” lights, two sound speakers and Auto Door
  • Cables, connectors and power supply
  • USB Hub (for multiple station GEMINI configurations)

GEMINI Optional Components

  • Air puff stimulation unit (AIRSTIM)
  • Additional test stations
  • Mouse passive avoidance start box
  • Grid floors (for rats or mice)
  • Shock Level Tester

 

產品規格

Dimensions

Outside: 26”(W) x 13”(D) x 17 1⁄4” (H) Inside: 9 1⁄2”(W) x 8”(D) x 8”(H) (each side)

Weight

35 lbs.

Material Composition

Acrylic and aluminum, stainless steel (Gate)

Maximum # Stations

8

# of Photobeams

16 infrared per enclosure

Photobeam Spacing

1”

Standard Cable Length

8 feet

Stimuli Options

Cue lights, house lights, sound, shock, gate

Color Options

Black

Stainless Steel Grids

28 for rats, 62 for mice

Q: What does the Gemini mouse start box do?

A: The mouse start box makes your test more consistent because it reduces the size of the start chamber. This more readily orients the mouse toward the shock (dark) chamber, and reduces the time to shock (dark) chamber entry.

Q: Why am I not getting the shock to work on Gemini?

A: The selector switch on the front of the Gemini unit may not be set to ‘manual mode’.

 
 

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